Anti-hypertensive Drug
Antihypertnesive Drug: Ganglion blocking agents: these drugs blocks the transmission in the autonomic ganglia (either sympathetic or parasympathetic) but we don't currently use these drugs, because of the large adverse reactions resulted from them (e.g., Trimetaphan). Adrenergic neuron Blocking: These agents prevent the release of norepinephrin and they reduce the contraction of the smooth muscle (e.g., Debrisoquine) they are not commonly used. Drugs that interfere with norepinephrine storage (Reserpine): They are commonly used in practice although they cause reduction or depletion of norepinephrin. As a result; they reduce the peripheral vascular resistance. They affect the Central Nervous system causing Sedation, depression, Parkinson- Like Syndrome and Postural hypotension which is also common. Adrenoceptor antagonists or blcokers: they antagonize the action of catecholamine at alpha and beta receptors what do they do? they reduce the cardiac ...